Heather L. Read

Curriculum Vitae

 

Department of Psychology, Assistant Research Professor

406 Babbidge Road

University of Connecticut U-20

Storrs, CT 06269-1020

 

office phone: 860-486-4108

Email: heather.read@phy.ucsf.edu

    URL: http://keck.ucsf.edu/~blondie

 

 

Professional Interests:

 

· Neural Basis of Auditory Perception and Cortical Plasticity – Optical imaging of cortical acoustic feature representations in a genetic mouse model of central nervous system based hearing impairments (intramural funding pending).

· Clinical Applications –Developing diagnostic tools to identify subtle hearing impairments that can underlie learning deficits (funded Project III, NICHD http://www.hd20806.net/). 

· Biomedical Signal Processing – Reverse correlation & white noise analysis to explore sensory processing from cellular to whole animal systems; computational models of neural networks (funded NICHD and pending NIDCD). 

· Neural Basis of Cross-modal Sensory Perception Psychophysics of structure-from-motion perception in humans and macaques.  Gain fields generated by convergent visual and oculomotor cues in macaques while performing a structure-from-motion descrimination task (post-doctorate studies).

 

Education:

 

· Ph. D. - Loyola University Stritch School of Medicine (1991), Pharmacology

· B.S. - Texas A & M University Biochemistry & Biophysics.

 

Post-graduate Research Experience:

 

Keck Center for Integrative Neuroscience, University of California, San Francisco.· Spectro-temporal and topographic acoustic feature encoding in auditory cortex, (1996-2002,  URL address: http://keck.ucsf.edu/~blondie)

Center For Molecular & Behavioral Neuroscience, Rutgers, The State University, Newark.· Visual and oculomotor feature encoding and psychophysics in awake macaques (1991-1996, URL address: http://www.cmbn.rutgers.edu)

 

 

 

Academic Honors and Awards:

 

·     Marine Biological Laboratory Fellow,

Neural Systems and Behavior at Woods Hole, MA, 1986.

·     Loyola University Medical School

Schmitt Dissertation Merit Award, IL 1991

·    Loyola University Medical School

Merit Graduate Fellowship, 1988-1991.

Recent Presentations:

 

·     CNS Biennial Symposium New York University, 2001

Processing the Auditory Environment.  NY, USA.

·     Juan March Foundation Symposium, 2002

Structure of the Cortical Microcircuit.  Madrid, Spain.

·    Neural Information Processing Systems (Workshop Speaker), 2002

Thalamocortical Processing in Audition and Vision, Whistler, BC.

http://keck.ucsf.edu/~blondie/Reprints/ARO2003Handout.pdf

 

·       

 

Teaching Experience:

 

· Course Director & Lecturer: “Sensation and Perception” University of Connecticut undergraduate course (2002-3)

· Guest Lecturer: "Auditory Neurophysiology" Rutgers, The State University, Newark NJ (1999).

· Guest Lecturer: "Principles of Pharmacology" Loyola University, Evanston IL (1990).

· Course Director & Lecturer: "Human Physiology" University Texas, San Antonio Tx (1986).


 

Funding:

Extramural

· NICHD (National Institute of Child Health and Human Development)

“Animal Models for Learning Disability: Acoustic mapping and connectivity. “ Heather Read, Principle Investigator; $1,200,000 (Total+Indirects)

URL:  http://www.hd20806.net/

Start Date: September, 2002    End Date: September, 2006

· NIDCD (National Institute of Deafness and other Communication Disorders) “Spectro-Temporal Integration Mechanisms for Sound Source Detection.”

 Heather Read, Co-Principle Investigator 

Submitted February 1, 2003

Intramural

· June 2002: University of Connecticut

 large sound attenuation chamber grant $14,000

· February 2003:

 Optical Imaging System grant $25,000 Submitted January, 2003  (pending).

 

Selected Publications (http://keck.ucsf.edu/~blondie/Reprints):

 

Armstrong, D.L., Read, H.L., Cork, A.E., Montemayor, F. and Wayner, M.J.  Effects of iontophoresis application of trimethyltin on spontaneous neuronal activity in mouse hippocampal slices.  Neurobehavioral Toxicology and Teratology. 8: 637-641 (1986).

Disterhoft, J.F., Golden, D.T., Read, H.L., Coulter, D.A. and Alkon, D.L.  AHP reductions in rabbit hippocampal neurons during conditioning correlate with acquisition of the learned response. Brain Res. 462: 118-125 (1988).

Minota, S., Miyazaki, T., Wang, M.Y., Read, H.L. and Dun, N.J. Glycine potentiates NMDA responses in rat hippocampal CA1 neurons. Neuroscience Letters. 100: 237-242 (1989).

Read, H.L., Kiraly, M. and Dun, N.J. Serotonin differentially affects synaptic potentials evoked in the rat cerebral cortical slice. Eur. J. Pharmac. 183: 1383 (1990).

Siegel, R.M. and Read, H.L., Models of the temporal dynamics of visual processing. J. Statistical Physics. 70:297-308 (1993).

Read, H.L., Beck, S.G., and Dun, N.J., Serotonergic suppression of interhemispheric cortical synaptic potentials, Brain Res. 643: 17-18 (1994).

Siegel, R.M. and Read, H.L., Analysis of optic flow in the monkey parietal area 7a.  Cerebral Cortex. 7: 327-346 (1997).

Read, H.L. and Siegel, R.M., Modulation of responses to optic flow in area 7a by retinotopic and oculomotor cues in monkey. Cerebral Cortex 7: 647-661 (1997).

Read, H.L. and Siegel, R.M., On the origins of aperiodicities in sensory neuron entrainment. Neuroscience. 75(1): 301-344 (1998).

Siegel, R.M. and Read, H.L. (2001) Deterministic dynamics emerging from a cortical functional network., Neural Networks 14: 697-713 (2001).

Miller, L.M., Escabí, M.A., Read, H.L. and Schreiner, C.E. Functional convergence of response properties in the auditory thalamocortical system Neuron 32: 151-160 (2001).

Read, H.L., Winer, J.A. and Schreiner, C.E. Intrinsic connections associated with spectral tuning in cat auditory cortex. PNAS. 98: 80420-8047 (2001).

Miller, L.M., Escabí, M.A., Read, H.L. and Schreiner, C.E. Spectro-temporal receptive fields in the lemniscal auditory thalamus and cortex.  J. Neurophysiol 87: 516-527 (2002).

Read, H.L., Escabí, M.A., Miller, L. , Schreiner, C.E. and Winer, J.A., Constructive versus inherited thalamocortical convergence patterns.,  in preparation (2003).

Read, H.L., Escabí, M.A., Nauen, D., Schreiner, C.E. and Winer, J.A., Iso-frequency thalamocortical projection patterns to central versus dorsal primary auditory cortex.,  in preparation (2003).

Read, H.L., Escabí, M.A., Miller, L.M. and Schreiner, C.E., Modular organization of spectral and temporal receptive field properties in primary auditory cortex., in preparation (2003). 

Escabi M.A., Read H.L., Miller, LM., et al. Contrast sensitivity in cat infererior colliculus. J Neurophysiol. In review.

 

 

 

Book Chapters and Reviews

 

Disterhoft, J.F., Read, H.L., and Akase, E. Hippocampal involvement in rabbit eyeblink conditioning. In: Synaptic Plasticity in the Hippocampus, edited by H.L. Haas and G. Buzsaki, Springer Verlag, Berlin, 196-197 (1988).

Siegel, R.M. and Read, H.L., Temporal processing in the visual brain, Annals of the NY Academy of Sciences. 682:171-178 (1993).

Siegel, R.M. and Read, H.L., Construction and representation of visual space in the inferior parietal lobule.  Cerebral Cortex , Vol. 12, eds. Rockland et al., Plenum Press, NY (1997).

Benasich, A.A. and Read, H.L., Representation: Picture or Process? In:  Theoretical perspectives in the development of representational (symbolic) thought.  Mahwah, NJ:  Lawrence Erlbaum Ass., Inc., 33-160 (1999).

Schreiner, C.E., Read, H.L. and Sutter, M.L. Modular organization of frequency integration in primary auditory cortex. Annu. Rev. Neurosci. 23: 501-529 (2000).

Fitch R. H., Read, H.L. and Benasich, A.A.  Neurophysiology of speech perception in normal  and impaired systems. In Physiology of the Ear, 2nd edition, A.F. Jahn & J. Santos-Sachi (Eds.).  Singular Thompson Learning, 651-671 ed. (2001).

Read, H.L., Winer, J.A. and Schreiner, C.E. Functional architecture of auditory cortex.  Current Opinions Neurobiol Aug;12:433-40 (2002).


 

References:

 

Dr. Christoph Schreiner, Associate Professor 

Keck Center for Integrative Neuroscience                    

University of California at San Francisco                   

513 Parnassus Ave., HSE-824                                                   

San Francisco, CA 94143-0732 513                              

Phone (415) 476-2591                                          

e-mail: chris@phy.ucsf.edu                                   

http://www.ucsf.edu/neurosc/faculty/neuro_schreiner.html

 

 

 

Dr. Jeffery Winer, Professor

Dept. Molecular and Cell Biology

University of California Berkeley

Rm 289, LSA

Berkeley, CA 94720-3210

Phone (510) 642-8227

e-mail: jawiner@socrates.Berkeley.edu

http://mcb.berkeley.edu/faculty/NEU/winerj.html

 

 

Dr. Michael Merzenich, Co-Chair

Dept. Otolaryngology

University of California, San Francisco

513 Parnassus Ave., HSE-828                                                   

San Francisco, CA 94143

Phone (415) 476- 9025

e-mail:  merz@phy.ucsf.edu

http://www.ucsf.edu/neurosc/faculty/neuro_merzenich.html

 

Dr. Ralph Siegel, Associate Professor              

Center for Molecular & Behavioral Neuroscience                                          

Rutgers University

Newark NJ   07042           

phone: (201) 648-1080 x3261                                                     

e-mail: siegel@cortex.rutgers.edu                         

http://ins.rutgers.edu/