Neuroscience Graduate Program at UCSF
NS240 - Fall 2009
Neurobiology of Vision
Course Directors:
Michael Stryker, email: stryker@phy.ucsf.edu
Jonathan Horton, email: hortonj@vision.ucsf.edu
Prerequisite: NS201 or permission of the course director.
First Class: Wednesday, September 16, 2009
Classes are held in S157, Parnassus. (unless noted otherwise)
Please see schedule for dates and times.
Attendance is expected (for those taking the course for credit).
Course Description:
Visual information processing by the retina and central nervous system. Molecular, electrophysiological, pharmacological, anatomical, and psychophysical approaches will be discussed. Topics may include synaptic interactions, diseases specific to the visual system, color vision, form perception, motion detection, and visual development.
Course Guidelines: (PDF)
General Plan:
Lectures: Wednesday evenings
Discussions: Monday evenings, open to registered students and, by permission of instructors, to others willing to participate fully
-2 to 4 relevant papers on topic
-A student leads discussion of each paper
-All students are expected to read and dissect each paper
Grading: Grades based on class discussion, leading discussions and attendance.
Enrolled students must attend each class. If travel plans conflict with attendance, see instructor in advance.
Course Materials:
Materials will be located at the right as they are added.
Class Schedule:
Date |
Time |
Location |
Subject |
Lecturer |
September |
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| Wednesday, 9/16/09 | 5:30-7:30pm | PH - S157 | Overview of the study of the central visual system, focusing on problems and methods | Michael Stryker |
Monday, 9/20/09 - No Class, Asilomar |
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| Wednesday, 9/23/09 | 5:30-7:30pm | PH - S157 | Inputs from eye to brain: Spatial and temporal properties of retinal ganglion cells | Jonathan Horton |
Monday, 9/28/09 - No Class, Yom Kippur |
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| Tuesday, 9/29/09 | 5:30-7:30pm | PH - S157 | Discussion on retinal ganglion cells. Note exceptional Tuesday meeting | |
| Wednesday, 9/30/09 | 5:30-7:30pm | PH - S157 | Lateral geniculate nucleus: Organization, temporal and spatial responses, function and role of cortical feedback | Jonathan Horton |
October |
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| Monday, 10/05/09 | 5:30-7:30pm | PH - S157 | Discussion on lateral geniculate nucleus | |
| Wednesday, 10/07/09 | 5:30-7:30pm | PH - S157 | Physiology of the primary visual cortex:. Receptive field properties: center/surround, simple, complex Columnar organization; modules Cortical cells and circuits Classic vs. nonclassic receptive fields. Intrinsic horizontal cortical projections within V1. | Michael Stryker |
| Monday, 10/12/09 | 5:30-7:30pm | PH - S157 | Discussion on V1 physiology | |
| Wednesday, 10/14/09 | 5:30-7:30pm | PH - S157 | Anatomy of the primary visual cortex: Retinotopic map; cortical magnification factor Inputs from LGB to cortical layers. | Jonathan Horton |
Monday and Wednesday, 10/19 and 10/21, No Class, SFN |
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| Monday, 10/26/09 | 5:30-7:30pm | PH - S157 | Discussion on Anatomy of Primary Visual Cortex | |
| Wednesday, 10/28/09 | 5:30-7:30pm | PH - S157 | Extrastriate Visual Cortex: Organization and maps of extrastriate cortex; Connections of extrastriate cortex; Motion, form, color vs. magno, parvo, konio ; Lesion studies ; Illusory contours ; Function of extrastriate cortex | Jonathan Horton |
November |
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| Monday, 11/02/09 | 5:30-7:30pm | PH - S157 | Discussion on Extrastriate Cortex | |
| Wednesday, 11/04/09 | 5:30-7:30pm | PH - S157 | Visual Psychophysics | Michael Stryker |
| Monday, 11/09/09 | 5:30-7:30pm | PH - S157 | Discussion on Visual Psychophysics | |
| Wednesday, 11/11/09 | 5:30-7:30pm | PH - S157 | Color Vision | Michael Stryker |
| Monday, 11/16/09 | 5:30-7:30pm | PH - S157 | Discussion on Color Vision | |
| Wednesday, 11/18/09 | 5:30-7:30pm | PH - S157 | Stereo, Motion, and Depth: Monocular Depth Clues; Size Constancy ; Retinal Disparity, Horopter, Panum’s Circle ; Random Dot Stereograms ; Depth encoding in V1, extrastriate regions ; Fusion, strabismus, binocular rivalry ; Direction Selective cells ; Visual pathways serving motion perception ; MT, and nearby visual areas: anatomy, connections, properties ; Area MT+: motion perception and optic flow | Jonathan Horton |
11/23/09 & 11/25/09 - No Class, Thanksgiving |
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| Monday, 11/30/09 | 5:30-7:30pm | PH - S157 | Discussion Section on Stereo, Motion, and Depth | |
December |
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| Wednesday, 12/02/09 | 5:30-7:30pm | PH - S157 | Form and Shape Identification | Michael Stryker |
| Monday, 12/07/09 | 5:30-7:30pm | PH - S157 | Discussion on Form and Shape Identification | |
| Wednesday, 12/09/09 | 5:30-7:30pm | PH - S157 | Development of retina -Maturation of neuronal circuits -Spontaneous waves before eye opening: Role and regulation Development of Central Visual System - Stryker Development of the geniculostriate pathway Maturation of visual function and receptive field properties. Formation of orientation and ocular dominance columns. Role of visual experience versus innate development. Amblyopia & Visual Deprivation – Horton Mechanisms and types of amblyopia. Anatomical and physiological correlates of amblyopia. Strabismus and visual suppression. |
Jonathan Horton and Michael Stryker |
| Wednesday, 12/09/09 | 7:30pm | PH - S157 | Jenny LaVail | Course Evaluation |
Courses
Course Materials
(UCSF Access Only)
September
09/16/09 - Wednesday
Course Overview
09/23/09 - Wednesday
Lecture
09/29/09 - Tuesday
Paper 1 - Diller
Paper 2 - Field
09/30/09 - Wednesday
Lecture
October
10/05/09 - Monday
Paper 1 - Briggs
Paper 2 - Reid & Shapley
10/07/09 - Wednesday
Lecture
10/12/09 - Monday
Paper 1 - Ozeki
Paper 2 - Zipser
10/14/09 - Wednesday
Lecture
10/26/09 - Monday
Paper 1 - Basole
Paper 2 - Priebe
10/28/09 - Wednesday
November
11/02/09 - Monday
Paper 1 - Lu
Paper 2 - Brewer
11/04/09 - Wednesday
Presentation
11/09/09 - Monday
Paper 1 - Levinson
Paper 2 - Watson 1980
Paper 3 - Watson 1981
11/11/09 - Wednesday
Presentation
11/16/09 - Monday
Paper 1 - Moutoussis
Paper 2 - Rudd
11/18/09 - Wednesday
Presentation
11/30/09 - Monday
Paper 1 - Nadler
Paper 2 - Nichols
December
12/02/09 - Wednesday
Lecture
12/07/09 - Monday
Paper 1 - Li
Paper 2 - Yamane
12/9/09 - Wednesday
Horton-Lecture
Stryker-Lecture