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Neuroscience Graduate Program at UCSF

NS240 - Fall 2009

NS240 - Fall 2009
Neurobiology of Vision

Course Directors:
Michael Stryker, email: stryker@phy.ucsf.edu
Jonathan Horton, email: hortonj@vision.ucsf.edu

Prerequisite: NS201 or permission of the course director.

First Class: Wednesday, September 16, 2009
Classes are held in S157, Parnassus. (unless noted otherwise)
Please see schedule for dates and times.
Attendance is expected (for those taking the course for credit).

Course Description:
Visual information processing by the retina and central nervous system. Molecular, electrophysiological, pharmacological, anatomical, and psychophysical approaches will be discussed. Topics may include synaptic interactions, diseases specific to the visual system, color vision, form perception, motion detection, and visual development.

Course Guidelines: (PDF)
General Plan:
Lectures: Wednesday evenings
Discussions: Monday evenings, open to registered students and, by permission of instructors, to others willing to participate fully
-2 to 4 relevant papers on topic
-A student leads discussion of each paper
-All students are expected to read and dissect each paper

Grading: Grades based on class discussion, leading discussions and attendance.
Enrolled students must attend each class.  If travel plans conflict with attendance, see instructor in advance.

Texbook References (PDF)

Course Syllabus (PDF)

Course Materials:
Materials will be located at the right as they are added.

Class Schedule:

Date
Time
Location
Subject
  Lecturer
September
Wednesday, 9/16/09 5:30-7:30pm PH - S157 Overview of the study of the central visual system, focusing on problems and methods Michael Stryker
Monday, 9/20/09 - No Class, Asilomar
Wednesday, 9/23/09 5:30-7:30pm PH - S157 Inputs from eye to brain: Spatial and temporal properties of retinal ganglion cells Jonathan Horton
Monday, 9/28/09 - No Class, Yom Kippur
Tuesday, 9/29/09 5:30-7:30pm PH - S157 Discussion on retinal ganglion cells.  Note exceptional Tuesday meeting  
Wednesday, 9/30/09 5:30-7:30pm PH - S157 Lateral geniculate nucleus:  Organization, temporal and spatial responses, function and role of cortical feedback Jonathan Horton
October
Monday, 10/05/09 5:30-7:30pm PH - S157 Discussion on lateral geniculate nucleus  
Wednesday, 10/07/09 5:30-7:30pm PH - S157 Physiology of the primary visual cortex:.  Receptive field properties: center/surround, simple, complex Columnar organization; modules Cortical cells and circuits Classic vs. nonclassic receptive fields. Intrinsic horizontal cortical projections within V1. Michael Stryker
Monday, 10/12/09 5:30-7:30pm PH - S157 Discussion on V1 physiology  
Wednesday, 10/14/09 5:30-7:30pm PH - S157 Anatomy of the primary visual cortex:  Retinotopic map; cortical magnification factor Inputs from LGB to cortical layers. Jonathan Horton
Monday and Wednesday,  10/19 and 10/21, No Class, SFN
Monday, 10/26/09 5:30-7:30pm PH - S157 Discussion on Anatomy of  Primary Visual Cortex  
Wednesday, 10/28/09 5:30-7:30pm PH - S157 Extrastriate Visual Cortex:  Organization and maps of extrastriate cortex; Connections of extrastriate cortex; Motion, form, color vs. magno, parvo, konio ; Lesion studies ; Illusory contours ; Function of extrastriate cortex Jonathan Horton
November
Monday, 11/02/09 5:30-7:30pm PH - S157 Discussion on Extrastriate Cortex  
Wednesday, 11/04/09 5:30-7:30pm PH - S157 Visual Psychophysics Michael Stryker
Monday, 11/09/09 5:30-7:30pm PH - S157 Discussion on Visual Psychophysics  
Wednesday, 11/11/09 5:30-7:30pm PH - S157 Color Vision Michael Stryker
Monday, 11/16/09 5:30-7:30pm PH - S157 Discussion on Color Vision   
Wednesday, 11/18/09 5:30-7:30pm PH - S157 Stereo, Motion, and Depth:  Monocular Depth Clues; Size Constancy ; Retinal Disparity, Horopter, Panum’s Circle ; Random Dot Stereograms ; Depth encoding in V1, extrastriate regions ; Fusion, strabismus, binocular rivalry ; Direction Selective cells ; Visual pathways serving motion perception ; MT, and nearby visual areas: anatomy, connections, properties ; Area MT+: motion perception and optic flow Jonathan Horton
11/23/09 & 11/25/09 - No Class, Thanksgiving
Monday, 11/30/09 5:30-7:30pm PH - S157 Discussion Section  on Stereo, Motion, and Depth  
December
Wednesday, 12/02/09 5:30-7:30pm PH - S157 Form and Shape Identification Michael Stryker
Monday, 12/07/09 5:30-7:30pm PH - S157 Discussion on Form and Shape Identification  
Wednesday, 12/09/09 5:30-7:30pm PH - S157 Development of retina -Maturation of neuronal circuits -Spontaneous waves before eye opening: Role and regulation
Development of Central Visual System - Stryker Development of the geniculostriate pathway Maturation of visual function and receptive field properties. Formation of orientation and ocular dominance columns. Role of visual experience versus innate development.
Amblyopia & Visual Deprivation – Horton Mechanisms and types of amblyopia. Anatomical and physiological correlates of amblyopia. Strabismus and visual suppression.
Jonathan Horton and Michael Stryker
Wednesday, 12/09/09 7:30pm PH - S157 Jenny LaVail Course Evaluation

Courses


Course Materials
(UCSF Access Only)

September

09/16/09 - Wednesday
Course Overview

09/23/09 - Wednesday
Lecture

09/29/09 - Tuesday
Paper 1 - Diller
Paper 2 - Field

09/30/09 - Wednesday
Lecture


October

10/05/09 - Monday
Paper 1 - Briggs
Paper 2 - Reid & Shapley

10/07/09 - Wednesday
Lecture

10/12/09 - Monday
Paper 1 - Ozeki
Paper 2 - Zipser

10/14/09 - Wednesday
Lecture

10/26/09 - Monday
Paper 1 - Basole
Paper 2 - Priebe

10/28/09 - Wednesday


November

11/02/09 - Monday
Paper 1 - Lu
Paper 2 - Brewer

11/04/09 - Wednesday
Presentation

11/09/09 - Monday
Paper 1 - Levinson
Paper 2 - Watson 1980
Paper 3 - Watson 1981

11/11/09 - Wednesday
Presentation

11/16/09 - Monday
Paper 1 - Moutoussis
Paper 2 - Rudd

11/18/09 - Wednesday
Presentation

11/30/09 - Monday
Paper 1 - Nadler
Paper 2 - Nichols


December

12/02/09 - Wednesday
Lecture

12/07/09 - Monday
Paper 1 - Li
Paper 2 - Yamane

12/9/09 - Wednesday
Horton-Lecture
Stryker-Lecture